Evidence That Moves Medical Innovation Forward
Who We Are
TTi Health Research & Economics is a specialized research and consulting organization focused on helping MedTech and precision medicine companies demonstrate value in today’s evidence-driven healthcare environment.
We partner with innovators to design and execute clinical studies, real-world evidence, and health economic analyses that support payer decision-making, health system adoption, and long-term market access.
Our work goes beyond proving safety and performance — we focus on generating decision-relevant evidence that answers the questions payers, providers, and value committees actually ask.
Why TTi
What sets TTi apart is not just what we do — it’s how we do it.
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Payer-first mindset: Evidence designed around coverage, reimbursement, and value assessment
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Senior-level engagement: Direct access to experienced leaders throughout every engagement
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MedTech-specific expertise: Strategies tailored to devices, diagnostics, and emerging technologies
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Pragmatic execution: Studies designed to be feasible, defensible, and delivered on commercial timelines
Our Approach
Healthcare adoption depends on more than innovation. It depends on evidence that aligns with how coverage, reimbursement, and purchasing decisions are made.
TTi designs payer-informed evidence strategies that connect:
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Clinical performance
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Real-world outcomes
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Economic value
We work across the product lifecycle — from late-stage clinical development through post-market growth — ensuring evidence strategies are feasible, defensible, and aligned with real-world decision frameworks.
Our team brings deep experience in medical devices, diagnostics, digital health, and emerging technologies, allowing us to tailor study designs and analyses to non-pharma pathways and evolving market expectations.
What We Do
We support clients through a comprehensive range of evidence generation and market access activities, including:
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Clinical trial design and enhancement to support payer-relevant endpoints
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Real-world and observational studies that extend clinical evidence into routine practice
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Health economic and outcomes research (HEOR), including budget impact and cost-effectiveness analyses
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Evidence strategy to support coverage applications, pricing, value dossiers, and health system review
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Strategic consulting across market access, reimbursement, and commercialization planning
Our goal is simple: to help clients generate evidence that supports confident decisions and sustained adoption.
There are specific needs we have as an organization, and I’ve found two things. One – that the team of people you have at TTi are very effective at helping me meet the needs that we have as an organization, and two, that we enjoy working with you.
The TTi team was always very reliable, thorough, and trustworthy. They do really good quality work and value you as a partner. You can trust that the work they do is going to meet your expectations. We’ve gotten a ton of mileage out of the asset they developed for us.
Prior to working with TTi we struggled to prove the cost-effectiveness of our technology. In fact, several less than favorable cost-effectiveness evaluations were published. TTi was confident that the previous study designs had biased the results and underestimated the value of our technology. Once we brought TTi on board we knew we were in the right hands. The results firmly established our technology as well below accepted thresholds of cost-effectiveness. If we could go back in time, we would hire TTi two years ago.
I enjoy the interactions a lot. People have been all extremely helpful. Many times I have come to you guys with requests that I need answers to last night and everybody is accommodating. We are always running 200 miles an hour over here so, people who understand that and make my job easier. I would say that you guys make me look good in front of my boss!
The TTi team provided us with smart, adaptable tools that could grow along with our company. Working with them enabled us to have a significant head start in developing and proving the value of our technology. We saved a lot of money and time by working with them from the very beginning.
It was such a relief to find in TTi a vendor that knew exactly what we needed, that understood our constraints, and that really gave a crap about helping us develop the right study to meet our needs and improve market access for our product. You guys are smart, decent folks, with the grittiness and resourcefulness to get the job done and get it done well.
Our contract payer relations team told us that these were the best CE tools they’d ever worked with. Within several months we saw a significant increase in the establishment of favorable coverage policies.
We were getting really frustrated and started to feel like the entire field was filled with folks who didn’t listen and wanted to charge a lot of money for it. But TTi listened to me from our first conversation and understood what my end points were immediately and understood what kind of help we needed. Sure enough, when we asked for a proposal they returned with a proposal that matched our needs and took into consideration the size of our company and our budget.
We thought conducting an additional prospective, longitudinal study was the only path forward. TTi solved our problem in a way that felt almost like magic to us, but the statistics were rigorous, have stood up to peer-review, and have made a tremendous impact on adoption of our technology.
Our project was not a standard, cookie-cutter model; it required getting in the weeds and really understanding the intricacies of the complex condition, the intervention, and the complications. I was impressed with the team’s professionalism and the high level of quality of the work products. This team represents excellence in what they do.
I’ve developed a lot of trust that when we set something out together, as a team, and establish a shared vision of what we’re looking for, I can trust that they will deliver.
We spoke with a couple of different vendors… TTi was the only group that understood our long-term research vision, but provided very practical, interim steps to take us down that path. They allowed us the flexibility to think and act as a smaller company. TTi has been an enormous force in helping us develop a robust research program. We greatly appreciate the collaboration.
We are really impressed with the level of experience and knowledge that Beth and April and the rest of the team have and it is certainly helpful to me as a CEO. When I walk into a board room or sit down with staff or investors they expect me to know all of these things all the time so it’s helpful to be able to have you behind us. It’s critical to our success as a company to have access to what you offer. I would highly recommend you to other folks.