Disease Models

Disease models allow you to present evidence and communicate value in an easily digestible format. They promote a better understanding of the disease and its burden, allow for the exploration of possible scenarios and comparison of interventions, and can demonstrate the potential of your technology to stakeholders.
Models of health and disease are used by policymakers to help inform policy and regulatory decisions.
Disease modeling can play an important role in developing technology for both chronic and infectious diseases.

Efficacy of the disease model and its scientific robustness are dependent on model choice and adherence to assumptions governing use of the chosen model.
Disease simulation models can be leveraged across your pipeline and development cycle.
The disease illness model and the continuum of chronic disease model are different frameworks for understanding disease that can inform the underlying assumptions and inputs for your disease model.

With our advanced knowledge of modeling software and state-of-the-art modeling capabilities, our experts can perform disease modeling upon which data from alternative treatments can be layered to permit preliminary explorations of both the clinical and cost effectiveness of your technology, then definitive cost effectiveness assessments as your clinical trial data becomes available.
Our models can help to explain the onset of disease caused by more than one factor to communicate the value of risk reduction and preventive measures using a multi-causation disease model; describe the transmission of infectious disease, estimate the probability of new infection, and communicate the value of risk reduction using a disease spread model; depict the incidence, time course of disease status and severity over time, and communicate the value of interventions using a disease progression model; represent the care structure surrounding your target indication including patient pathways, treatment modes, and the mix of resources required to treat your patient populations and explore possible scenarios through discrete event simulation; and more.
Our models are validated and parameterized through in-depth review of literature, consultation with expert panels, and derivation of data from supplemental sources.

Insights

Assessment of the Cost-Effectiveness of Hypertension Management Strategies in Persons with Chronic Kidney Disease (CKD) [Centers for [...]